You really can't appreciate how thin the phone is until you hold it your hand. Ironically, I think the larger size makes the thickness stand out. The Nexus 6P is not much thinner than my Moto X, yet in my hand it feels thinner.
Given how long large screen phones have existed, I am shocked that there are a lot of widgets that don't allow you to adjust their size. I mostly use 4x1 size widgets, which span the width of the screen on the Moto X but are a little short on the Nexus 6P. Perhaps I am being anal, but it drives me nuts that the widgets don't look centered, and the Google home screen layout does not allow me to manually center widgets.